Thottakam, B., Webster, N. R., Allen, L., Columb, M. O., & Galley, H. F. (2020). Melatonin Is a Feasible, Safe, and Acceptable Intervention in Doctors and Nurses Working Nightshifts: The MIDNIGHT Trial. Frontiers in psychiatry, 11, 872. https://doi.org/10.3389/fpsyt.2020.00872
In this article, a trial study was performed for melatonin sleep intervention in 25 healthcare participants working night shifts to determine if it is a safe and feasible intervention for performing a larger study. Results of the trial design were promising enough to be feasible and safe for a larger definitive study. These results include improved concentration and attention in the double digit task during melatonin administration.