To make sure that CBD arrives in the gut in its active form, our solution is to incorporate it in liposomes, which are small, carefully designed phospholipid vesicles
Cannabidiol (CBD) is one of the several natural active ingredients of the Cannabis plant. It differs from tetrahydrocannabinol (THC) in that it lacks the well-known psychoactive effects .
Why Liposoma’s Liposomal CBD?
CBD is completely insoluble in water, poorly dissolves in alcohol and only dissolves well in oil. To be optimally absorbed in the intestines, CBD must be presented as individual molecules to the intestinal epithelial cells responsible for uptake of nutrients. In theory products with oily solutions could achieve this, but in practice the break up of an oil by the intestinal fluid and the process of dispersing it into tiny droplets ready for absorption is not straightforward and there are reports of poor bioavailability and high variability in uptake of CBD from oil products .
To make sure that CBD arrives in the gut in its active form, a solution is to incorporate it in liposomes, which are small, carefully designed phospholipid vesicles that form very stable dispersions in water . The phospholipids constitute a bilayer structure in which the CBD molecules can be safely kept dissolved, while at the same time they act as surfactants that help present them to the intestinal epithelial cells in the most optimal manner.
What is more, the liposomal supplements that are engineered by LIPOSOMA contain specific additives based on Vitamin E in the bilayer that further increase liposome stability and help protect its vulnerable contents against oxidation as well as attack of gastric fluids and enzymes.
“Our liposomal vitamins and other nutraceuticals are available as raw materials, capsules, liquids and many other tailored solutions. “
LIPOSOMA Nutraceuticals; experts in liposomes
LIPOSOMA manufactures branded and white label liposomal supplements.
Our high-end liposomal nutraceuticals are guaranteed by the academic qualifications of our team and its commitment to scientific excellence.
Our liposome technology offers many advantages for nutritional supplement producers, the food sector and consumers. Our liposomal vitamins and other nutraceuticals are available as raw materials, capsules, liquids and many other tailored solutions.
Would you like to learn more? Give us a call at 0031 20 237 36 00
 Izzo, A. A., Borrelli, F., Capasso, R., Di Marzo, V., & Mechoulam, R. (2009). Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. Trends in pharmacological sciences, 30(10), 515-527.
 Zgair, A., Wong, J. C., Lee, J. B., Mistry, J., Sivak, O., et al. (2016). Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines. American journal of translational research, 8(8), 3448.
 Akbarzadeh, A., Rezaei-Sadabady, R., Davaran, S., Joo, S. W., Zarghami, N., et al. (2013). Liposome: classification, preparation, and applications. Nanoscale research letters, 8(1), 102.