DHA and Lutein are loaded into the liposomes to make them work synergistically, providing a unique combination for vision health
DHA and Lutein
Docosahexaenoic acid (DHA) is an important omega 3 fatty acid that plays a role in brain functioning [1-3]. In addition, DHA is beneficial for vision health [1-3], as it plays a role in eye development, while it helps to maintain retinal function [4] Lutein is a naturally occurring carotenoid that, together with zeaxanthin, constitutes the macula of the eye, the region responsible for clear, central vision and colour perception [5,6]. Lutein can be consumed from our diet, as it naturally occurs in for example fruits, vegetables and egg yolk [7,8].
Benefits of liposomal DHA + Lutein
Our White label DHA + Lutein product is packed in liposomes. Liposomes feature a phospholipid bilayer shell that can hold and protect delicate health ingredients against premature degradation [9]. Phospholipids can also help make DHA and lutein better available for intestinal absorption [10,11]. DHA and lutein together incorporated in the liposomes can also help make them work synergistically, providing a unique combination for vision health [12].
LIPOSOMA’s DHA + Lutein comes in a uniquely freeze-dried form
While most other DHA- and lutein-containing health supplements are oil-based or provided as an aqueous dispersion, LIPOSOMA’s liposomal DHA and Lutein supplement also features the benefits of a freeze-dried powder formulation for improved storage stability. LIPOSOMA has developed a freeze drying technique for its liposomal supplements that allows both for freezing and drying without damaging the vesicular bilayer structure of the liposome. This means that after reconstitution in a water environment (e.g. in the intestinal lumen) the liposomes reappear the way they were made without chemical or morphological changes.
Freeze-drying not only ensures long-term physical and chemical stability but also makes LIPOSOMA’s supplements compatible with so-called Delayed Release capsules that only open after passage through the stomach, avoiding the detrimental gastric environment. This is something any DHA food supplement product can significantly benefit from but this cannot be achieved with most other (oil-based) products, including the DHA-enriched oils.
With our liposomal supplement we provide you a therapeutic, bioavailable vision health supplement that allows the body to better utilize its numerous benefits that are being studied and documented by many scientists all over the world.
“Our liposomal vitamins and other nutraceuticals are available as raw materials, capsules, liquids and many other tailored solutions. “
LIPOSOMA Nutraceuticals; experts in liposomes
LIPOSOMA manufactures branded and white label liposomal supplements.
Our high-end liposomal nutraceuticals are guaranteed by the academic qualifications of our team and its commitment to scientific excellence.
Our liposome technology offers many advantages for nutritional supplement producers, the food sector and consumers. Our liposomal vitamins and other nutraceuticals are available as raw materials, capsules and many other tailored solutions.
Would you like to learn more? Give us a call at 0031 20 237 36 00
Sources
[1] Harris WS, Baack ML. Beyond building better brains: bridging the docosahexaenoic acid (DHA) gap of prematurity. J Perinatol. 2015; 35(1):1-7.
[2] Bazan NG, Musto AE, Knott EJ. Endogenous signaling by omega-3 docosahexaenoic acid-derived mediators sustains homeostatic synaptic and circuitry integrity. Mol Neurobiol. 2011; 44(2): 216-22.
[3] Bazan NG, Molina MF, Gordon WC. Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer’s, and other neurodegenerative diseases. Annu Rev Nutr. 2011; 31: 321-51.
[4] ] Scientific Opinion on the substantiation of health claims related to docosahexaenoic acid (DHA) and maintenance of normal (fasting) blood concentrations of triglycerides (ID 533, 691, 3150), protection of blood lipids from oxidative damage (ID 630), contr. (2010). EFSA Journal, 8(10), p.1734.
[5] Sommerburg, O., Siems, W.G., Van Kuijk, F.J. (2000). Localization of carotenoids in different eye tissues. BioFactors (Oxford, England) 11(1-2), 3-6.
[6] Manayi, A., Abdollahi, M., Raman, T., Nabavi, F.S., Habtemariam, S., Daglia, M., Nabavi, S.M. (2016). Lutein and cataract: from bench to bedside. Critical Reviews in Biotechnology, 36(5), 829-839. doi:10.3109/07388551.2015.1049510
[7] Calvo, M.M. (2005). Lutein: a valuable ingredient of fruit and vegetables. Critical Reviews in Food Science and Nutrition 45(7-8), 671-96.
[8] Perry, A., Rasmussen, H., Johnson, E. (2009). Xanthophyll (lutein, zeaxanthin) content in fruits, vegetables and corn and egg products. Journal of Food Composition and Analysis 22, 9–15.
[9] Akbarzadeh, A., Rezaei-Sadabady, R., Davaran, S., Joo, S. W., Zarghami, N., Hanifehpour, Y., … & Nejati-Koshki, K. (2013). Liposome: classification, preparation, and applications. Nanoscale research letters, 8(1), 102.
[10] Tan, C., Xue, J., Lou, X., Abbas, S., Guan, Y., Feng, B., Zhang, X., Xia, S. (2014a). Liposomes as delivery systems for carotenoids: comparative studies of loading ability, storage stability and in vitro release. Food & Function 5(6), 1232-40. doi: 10.1039/c3fo60498e.
[11] Tan, C., Zhang, Y., Abbas, S., Feng, B., Zhang, X., Xia, S. (2014b). Modulation of the carotenoid bioaccessibility through liposomal encapsulation. Colloids and Surfaces B: Biointerfaces 123, 692-700.
[12] DiSilvestro, R. A., Thomas, S., Harrison, E., & Epitropoulos, A. (2015). A pilot comparison of phospolipidated lutein to conventional lutein for effects on plasma lutein concentrations in adult people. Nutrition journal, 14(1), 104.