Scientific literature suggests a role for EGCG in cardiovascular health and protection against oxidative damage
Liposomal EGCG
LIPOSOMA offers white label liposomal EGCG supplements. These supplements feature high-quality EGCG encapsulated in liposomes, bringing it closer to delivering on its health promises. Scientific literature suggests a role for EGCG in cardiovascular health*, protection against oxidative damage* and more. Our liposomal EGCG supplements are available as capsules, liquids and a water-soluble powder. Moreover, we are open to discuss other tailored solutions. The quality of our high-end liposomal EGCG supplements is guaranteed by our professionally trained team and their commitment to scientific excellence.
Health benefits of EGCG
Epigallocatechin-3-gallate (EGCG) is a natural health ingredient present in green tea and other natural sources such as fruits and cacao. Catechins including EGCG are thought to be responsible for the beneficial health effects that are suggested for green tea in literature* [1,2]. For example, EGCG has been associated with managing weight* [3,4] and blood glucose levels* [5]. Furthermore, evidence in both human and animal studies suggests that EGCG plays a role in cardiovascular health* [6-8]. Finally, EGCG is suggested to have an antioxidant function*, because it scavenges free radicals and oxidants [9]. This helps protect body tissues and cells from oxidative damage*.
*These claims are currently on hold for revision by EFSA and not yet approved.
Why take liposomal EGCG?
After oral administration, EGCG needs to be taken up in the gut in order to execute its suggested health functions. At LIPOSOMA, we design and produce liposomal supplements, which maximize the chance of uptake of delicate natural health ingredients, including EGCG, after oral intake. Being a substance vulnerable for degradation, EGCG benefits from protection by the liposomes in the gastrointestinal tract, making sure the active form remains preserved before it is absorbed by the body [10-13].
“Our liposomal vitamins and other nutraceuticals are available as raw materials, capsules, liquids and many other tailored solutions. “
LIPOSOMA Nutraceuticals; experts in liposomes
LIPOSOMA manufactures branded and white label liposomal supplements.
Our high-end liposomal nutraceuticals are guaranteed by the academic qualifications of our team and its commitment to scientific excellence.
Our liposome technology offers many advantages for nutritional supplement producers, the food sector and consumers. Our liposomal vitamins and other nutraceuticals are available as raw materials, capsules, liquids and many other tailored solutions.
Would you like to learn more? Give us a call at 0031 20 237 36 00
Sources
[1] Khan, N., Mukhtar, H. (2018). Tea Polyphenols in Promotion of Human Health. Nutrients 11(1). pii: E39. doi: 10.3390/nu11010039.
[2] Wolfram, S. (2007). Effects of green tea and EGCG on cardiovascular and metabolic health. Journal of the American College of Nutrition, 26(4), 373S-388S.
[3] Wu, C. H., Lu, F. H., Chang, C. S., Chang, T. C., Wang, R. H., & Chang, C. J. (2003). Relationship among habitual tea consumption, percent body fat, and body fat distribution. Obesity research, 11(9), 1088-1095.
[4] Rains, T.M.; Agarwal, S.; Maki, K.C. (2011). Antiobesity effects of green tea catechins: A mechanistic review. Journal of Nutritional Biochemistry 22(1), 1-7.
doi: 10.1016/j.jnutbio.2010.06.006.
[5] Hosoda, K., Wang, M. F., Liao, M. L., Chuang, C. K., Iha, M., Clevidence, B., & Yamamoto, S. (2003). Antihyperglycemic effect of oolong tea in type 2 diabetes. Diabetes care, 26(6), 1714-1718.
[6] Kuriyama, S., Shimazu, T., Ohmori, K., Kikuchi, N., Nakaya, N., Nishino, Y., … & Tsuji, I. (2006). Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: the Ohsaki study. Jama, 296(10), 1255-1265.
[7] Chen, K., Chen, W., Liu, S.L., Wu, T.S., Yu, K.F., Qi, J., Wang, Y., Yao, H., Huang, X.Y., Han, Y., Hou, P. (2018). Epigallocatechingallate attenuates myocardial injury in a mouse model of heart failure through TGF‑β1/Smad3 signaling pathway. Molecular Medicine Reports 17(6), 7652-7660. doi: 10.3892/mmr.2018.8825. Epub 2018 Mar 29.
[8] Zhang, Q., Hu, L., Chen, L., Li, H., Wu, J., Liu, W., Zhang, M., Yan, G. (2018). (-)-Epigallocatechin-3-gallate, the major green tea catechin, regulates the desensitization of β1 adrenoceptor via GRK2 in experimental heart failure. Inflammopharmacology 26(4), 1081-1091. doi: 10.1007/s10787-017-0429-x.
[9] Erba, D., Riso, P., Bordoni, A., Foti, P., Biagi, P. L., & Testolin, G. (2005). Effectiveness of moderate green tea consumption on antioxidative status and plasma lipid profile in humans. The Journal of nutritional biochemistry, 16(3), 144-149.
[10] Kohri, T., Matsumoto, N., Yamakawa, M., Suzuki, M., Nanjo, F., Hara, Y., Oku, N. (2001). Metabolic fate of (-)-[4-H-3]epigallocatechin gallate in rats after oral administration. Journal of Agricultural and Food Chemistry 49, 4102–4112.
[11] van’t Slot, G., Humpf, H. U. (2009). Degradation and metabolism of catechin, epigallocatechin-3-gallate (EGCG), and related compounds by the intestinal microbiota in the pig cecum model. Journal of Agricultural and Food Chemistry 57, 8041–8048.
[12] Zhu, Q.Y., Huang, Y., Tsang, D., Chen, Z.Y. (1999). Regeneration of Alpha-Tocopherol in Human Low-Density Lipoprotein by Green Tea Catechin. Journal of Agricultural and Food Chemistry 47(5), 2020-5. doi: 10.1021/jf9809941.
[13] Fang, J.Y., Lee, W.R., Shen, S.C., Huang, Y.L. (2006). Effect of Liposome Encapsulation of Tea Catechins on Their Accumulation in Basal Cell Carcinomas. Journal of Dermatological Science 42(2), 101-9. doi: 10.1016/j.jdermsci.2005.12.010.