Vitamin D3 is essential for healthy bones and teeth, in addition to its role in preventing weakness of the immune system and muscles
Liposomal vitamin D3
Liposoma offers white label liposomal vitamin D3 supplements. These supplements include high-quality vitamin D3, packed in a liposome, providing you with this vitamin’s numerous health effects. Vitamin D3 is essential for healthy bones and teeth, in addition to its role in preventing weakness of the immune system and muscles. Our liposomal vitamin D3 supplements help maintain D3 levels at the right level. Supplements are available as capsules, liquids and a water-soluble powder. Moreover, we are open to discuss other tailored solutions. Our high-end liposomal D3 supplements are guaranteed by the academic qualifications of our team and its commitment to scientific excellence.
Health benefits vitamin D3
Vitamin D3 (cholecalciferol) is one of the few vitamins our body can synthesize by itself. Its production is a complex process requiring exposure of skin to the sunlight. Other sources of vitamin D3 are sea food, meat and egg yolk. Vitamin D plays a vital role in the uptake and metabolism of calcium and phosphorus from our intestines [1].These processes are crucial for healthy bones and teeth and hence for restricting osteoporosis in elderly and for preventing rachitis in children. It is also recommended for pregnant and lactating women to increase their vitamin D3 levels due to the transmission of the vitamin from mother to infant. Furthermore, vitamin D3 deficiency is also related to weakness of the immune system, decreased muscle strength [2] and premenstrual syndrome symptoms [3].
Why take vitamin D3 supplements?
There are multiple factors that can lead to a vitamin D deficiency. A contemporary indoor lifestyle often results in insufficient skin contact with sunlight, even though sunlight is the main source of vitamin D3 [4]. Furthermore, the production of vitamin D3 is lower in people with a coloured skin [2,5]. Especially during darker months this can lead to a deficiency. People who do not get skin contact with the sun do not produce vitamin D3 by themselves and need to obtain it via another source. The alternative source of vitamin D3, natural food sources, contains little amounts of this vitamin. Hence the lack of exposure to sunlight is difficult to compensate with natural food sources [4]. Supplementation of vitamin D3 is a simple way to prevent adverse effects of low concentrations of this nutrient. It is also recommended for pregnant and lactating women to increase their vitamin D3 levels due to the transmission of the vitamin from mother to infant [1,2,6,7].
Vitamin D3 and COVID-19
The link between vitamin D3 deficiency and COVID-19 is currently extensively studied. So far, two meta-analyses have shown that vitamin D supplementation is safe and effective in preventing acute respiratory tract infections [8,9], making vitamin D an interesting substance to investigate in the prevention of COVID-19. Indeed, in a recent pilot-study it was found that patients with COVID-19 who were supplemented with calcifediol, which is an activated form of vitamin D3, had significantly better disease outcomes [10]. Of the 50 patients that were supplemented with high doses of calcifediol in this study on top of standard-of-care, only one patient needed to be admitted to the ICU and none died, whereas of the 26 patients who only received standard-of-care 13 were admitted to the ICU and 2 died [10]. The promising role of vitamin D3 is further investigated, anticipating more solid evidence to appear in the near future further supporting the hypothesis that supplementation of vitamin D3 can help prevent COVID-19 and improve disease outcomes.
The benefits of liposomal vitamin D3
Vitamin D3 is poorly miscible in water and hence difficult to absorb by the body. Liposomes enhance the uptake in the body, and are capable of protecting the vitamin against harmful bodily processes [11]. For example, vitamin D3 is protected against oxidation and degradation when encapsulated in liposomes. These advantages combined lead to a higher bioavailability of vitamin D3, which means a higher chance of the vitamin reaching the target site. This makes liposomal vitamin D3 more effective than regular vitamin D3 [12].
“Our liposomal vitamins and other nutraceuticals are available as raw materials, capsules, liquids and many other tailored solutions. “
Liposoma Nutraceuticals; experts in liposomes
LIPOSOMA manufactures branded and white label liposomal supplements.
Our high-end liposomal nutraceuticals are guaranteed by the academic qualifications of our team and its commitment to scientific excellence.
Our liposome technology offers many advantages for nutritional supplement producers, the food sector and consumers. Our liposomal vitamins and other nutraceuticals are available as raw materials, capsules, liquids and many other tailored solutions.
Would you like to learn more? Give us a call at 0031 20 237 36 00
Sources
[1] Holick, M. F. (2006). Resurrection of vitamin D deficiency and rickets. The Journal of clinical investigation, 116(8), 2062-2072.
[2] Holick, M. F. (2007). Vitamin D deficiency. New England Journal of Medicine, 357(3), 266-281.
[3] Fatemi, M., Allahdadian, M., & Bahadorani, M. (2019). Comparison of serum level of some trace elements and vitamin D between patients with premenstrual syndrome and normal controls: A cross-sectional study. International Journal of Reproductive Biomedicine, 17(9), 647.
[4] Wilson, L. R., Tripkovic, L., Hart, K. H., & Lanham-New, S. A. (2017). Vitamin D deficiency as a public health issue: using vitamin D 2 or vitamin D 3 in future fortification strategies. Proceedings of the Nutrition Society, 76(3), 392-399.
[5] Durazo-Arvizu, R. A., Camacho, P., Bovet, P., Forrester, T., Lambert, E. V. et al. (2014). 25-Hydroxyvitamin D in African-origin populations at varying latitudes challenges the construct of a physiologic norm. The American journal of clinical nutrition, 100(3), 908-914.
[6] Hollis, B. W., & Wagner, C. L. (2004). Vitamin D requirements during lactation: high-dose maternal supplementation as therapy to prevent hypovitaminosis D for both the mother and the nursing infant. The American journal of clinical nutrition, 80(6), 1752S-1758S.
[7] Wagner, C. L., Hulsey, T. C., Fanning, D., Ebeling, M., & Hollis, B. W. (2006). High-dose vitamin D3 supplementation in a cohort of breastfeeding mothers and their infants: a 6-month follow-up pilot study. Breastfeeding Medicine, 1(2), 59-70.
[8] Jolliffe, D., Camargo, C. A., Sluyter, J., Aglipay, M., Aloia, J., Bergman, P., … & Gilham, C. (2020). Vitamin D supplementation to prevent acute respiratory infections: systematic review and meta-analysis of aggregate data from randomised controlled trials. medRxiv.
[9] Martineau, A. R., Jolliffe, D. A., Hooper, R. L., Greenberg, L., Aloia, J. F., Bergman, P., … & Goodall, E. C. (2017). Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. bmj, 356.
[10] Castillo, M. E., Costa, L. M. E., Barrios, J. M. V., Díaz, J. F. A., Miranda, J. L., Bouillon, R., & Gomez, J. M. Q. (2020). Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: A pilot randomized clinical study. The Journal of steroid biochemistry and molecular biology, 105751.
[11] Akbarzadeh, A., Rezaei-Sadabady, R., Davaran, S., Joo, S. W., Zarghami, N., et al. (2013). Liposome: classification, preparation, and applications. Nanoscale research letters, 8(1), 102.
[12] Chaves, M. A., Oseliero Filho, P. L., Jange, C. G., Sinigaglia-Coimbra, R., Oliveira, C. L. P. et al. (2018). Structural characterization of multilamellar liposomes coencapsulating curcumin and vitamin D3. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 549, 112-121.